I-GEN Cutting Edge News
Lezi zindaba ezisanda kubikwa kwabe-GEN (Genetic Engineering & Biotechnology News) zisho lokhoiziphathimandla zase-UK zinikeze imvume ku-Casgevy, i-CRISPR-Cas9 yokwelapha ngaphambili eyayaziwa ngokuthi i-exa-cel eyakhiwe yi-Vertex Pharmaceuticals and CRISPR Therapeutics.Kuyi-aisimemezelo esiyingqopha-mlando sensimu ye-CRISPR kanye nomphakathi we-sickle cell disease (SCD)..I-US Food and Drug Administration (FDA) kulindeleke ukuthi ilandele okufanayo emasontweni amathathu ezayo, njengoba ikhiphe idethi yesinqumo ngoDisemba 8. Esinye isinqumo mayelana nokwelashwa kwe-SCD ye-Bluebird bio kufanele size kamuva kuleyo nyanga. Ukugunyazwa kwe-UK kumenyezelwe yi-ejensi Elawula Imikhiqizo Yezokwelapha Nezempilo.ICRISPR-Cas9 ubuchwephesheizonikelaikhambi noma ukwelashwa okusebenzayo kwesifo se-sickle cell.
Isithombe esivela kuwebhusayithi ye-Genetic Engineering & Biotechnology News
Ulwazi MayelanaIsikelaCellDukukhululeka (SCD)
I-Sickle cell disease (SCD), eyaziwa nangokuthi i-sickle cell anemia, isifo sofuzo esithinta amangqamuzana egazi abomvu. Kuyisimo esizuzwe njengefa esibangelwa ukuguqulwa kofuzo lwe-HBB, oluhlanganisa ingxenye ye-hemoglobin, iphrotheni emangqamuzaneni abomvu egazi anesibopho sokuthwala umoya-mpilo kuwo wonke umzimba. Lokhu kuguqulwa kuholela ekukhiqizweni kwe-hemoglobin engavamile eyaziwa ngokuthi i-hemoglobin S (HbS).
Kubantu abanesifo se-sickle cell, i-hemoglobin engavamile ibangela ukuthi amangqamuzana egazi abomvu aqine, anamathele futhi amise okwe-crescent (afane nesikela). Lawa maseli angajwayelekile angabhajwa emithanjeni yegazi emincane, okuholela ezinkingeni ezihlukahlukene, okuhlanganisa ubuhlungu, i-anemia, ukulimala kwezitho zomzimba, kanye nobungozi obukhulu bokutheleleka.
Indlela Elula Yokuhlonza i-SingquzaCellDngenzela
I-Beijing Liuyi Biotechnology Co. Ltd (I-Liuyi Biotechnology) uye wasebenza ngokukhethekile ekukhiqizeni amathuluzi e-electrophoresis iminyaka engaphezu kwengu-50 neqembu lethu lochwepheshe lobuchwepheshe kanye nesikhungo se-R&D. Sinomugqa wokukhiqiza onokwethenjelwa nophelele kusukela ekuklanyweni kuya ekuhlolweni, kanye nendawo yokugcina impahla, kanye nokwesekwa kokumaketha. Imikhiqizo yethu eyinhloko i-Electrophoresis Cell (ithangi/igumbi), i-Electrophoresis Power Supply, i-Blue LED Transilluminator, i-UV Transilluminator, iGel Image & Analysis System njll.
I-Liuyi Bilotechnology yenza imodeli eyodwa yethangi le-electrophoresis elibizwa nge-cellulose acetate membrane elctrophoresis tank DYCP-38C engashintshwa ukuze kuhlaziywe izinhlobonhlobo ze-hemoglobin, okuhlanganisa nalezo ezihambisana nesifo se-sickle cell (SCD). Kuyindlela yendabuko nezomnotho ye-hemoglobin electrophoresis.
Uma unentshisekelo kule ndlela elula neyomnotho ye-electrophoresis, sicela uvakashele isiqephu sendatshana esilandelayo ukuze uthole amaphrothokholi nemihlahlandlela ye-hemoglobin electrophoresis ehlinzekwa ngabahloli bethu.
Ukuhlolwa kokuhlukanisa amaprotheni e-serum nge-Cellulose Acetate Membrane Electrophoresis
I-Beijing Liuyi biotechnology ibigxile ekukhiqizeni imikhiqizo ye-electrophoresis iminyaka engaphezu kwengu-50 yomlando e-China futhi inkampani ingahlinzeka ngemikhiqizo ezinzile nesezingeni eliphezulu emhlabeni jikelele. Ngeminyaka yokuthuthuka, kufanelekile ukukhetha kwakho!
Manje sifuna ozakwethu, kokubili ithangi le-OEM electrophoresis kanye nabasabalalisi bamukelekile.
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Izithenjwa
Isikhathi sokuthumela: Nov-21-2023